Ajax vs Inter Milan Betting Prediction, Tips & Preview

September 16, 2025
3 Minute Read

Our Ajax vs Inter Milan Prediction Sees Nerazzurri Snatch All Three Points in Amsterdam

Ajax and Inter Milan go head-to-head on Wednesday in UEFA Champions League action at the Johan Cruyff Arena. Inter, last season’s runners-up, would love to kick off their European campaign with three points on the road.

Champions League Betting Picks

Inter Milan Win & BTTS – 3.40

Marcus Thuram to Score Anytime – 2.60

Bet on Ajax vs Inter Milan

Can Chivu’s Boys Bounce Back After Two Defeats?

After a couple of tough years, Ajax were much better last season, finishing second in the Eredivisie to book their place in the Champions League for the first time since 2022. John Heitinga’s boys could be a dark horse in Europe this term.

Ajax have had a mixed bag of results at the start of this season, winning three and drawing two of their opening five Eredivisie games. They returned to action from the international break with a 3-1 home success over PEC Zwolle.

Inter have made a poor start in Serie A, collecting just three points from a possible nine. Cristian Chivu won his first league game in charge, guiding his side to a 5-0 home win against Torino. However, they have gone on to suffer back-to-back defeats to Udinese and Juventus.

Inter were magnificent in the Champions League last term, reaching the final before losing to Paris Saint-Germain. However, a lot has changed at the San Siro since then, with Chivu replacing Simone Inzaghi. How will Nerazzurri adapt to life under their new boss?

Ajax vs Inter Milan Betting Odds

Ajax may be the home team, but Heitinga’s side are the big underdogs against the Italian team. The home victory is priced at 4.10, while you can get the draw at 3.90.

Inter are desperate to respond to back-to-back league defeats, and the away win here is available at 1.80. Winning in Amsterdam is no easy task, but Chivu’s men will fancy their chances.

Ajax Win – 4.10

Draw – 3.90

Inter Milan Win – 1.80

View Latest Ajax vs Inter Milan Odds

Recent Ajax vs Inter Milan Head-to-Head Results

These two have not met since 2006, when they squared off in a two-legged Champions League Round of 16 tie. Inter won 3-2 on aggregate but were knocked out by Villarreal in the next round.

The pair also locked horns in the Champions League group stage in the 2002-03 season, with Inter winning both games. Nerazzurri picked up a 1-0 home victory and won 2-1 in the Dutch capital.

Ajax vs Inter Milan Betting Tips & Predictions

The Johan Cruyff Arena is a tough place to visit, but we fancy Inter to get back on track with a narrow away win. The away victory and both teams to score is worth a punt at 3.40.

Despite Inter’s sluggish start, Marcus Thuram has scored three goals in three games. The in-form Frenchman is available at 2.60 to score anytime in Amsterdam.

Champions League Betting Picks

Inter Milan Win & BTTS – 3.40

Marcus Thuram to Score Anytime – 2.60

View Latest Champions League Odds

Gareth Hinton

Gareth is an experienced sports betting writer, covering a range of sports. He can write all types of content, ranging from betting tips to in-depth match previews.

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