Six Nations Betting Predictions, Tips & Preview

Our Six Nations Prediction Sees Trio of Away Wins

The second round of 2025 Six Nations Championship fixtures take place this weekend. Italy and Wales kick the action off with a matchup in Rome, while England face France at Twickenham. On Sunday afternoon, Scotland and Ireland meet at Murrayfield.

Six Nations Betting Picks:

Wales Win – 3.00

France Win – 1.47

Ireland to Win -7.5 – 2.09

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Wales to Get Revenge in Rome

Italy and Wales are both looking to avoid finishing bottom in this year’s Six Nations. The Italians picked up a memorable win in Cardiff last year, but can the Dragons get revenge in Rome?

Wales started their tournament with a heavy 43-0 defeat in France, while Italy put up a brave fight in their 31-19 loss in Scotland. This fixture is getting harder to call, but we are backing Wales to nick a narrow win at the Stadio Olimpico (3.00).

Wales Win – 3.00

Bet on Italy vs Wales

French to Leave London with the Victory

The standout game of the round is Saturday’s showdown in London between England and France. Les Bleus may be the favourites, but the English are never an easy team to beat at Twickenham.  

The French were too hot for Wales to handle in game one, with Theo Attissogbe and Julien Marchand among the try scorers in a 43-0 mauling. England were narrowly beaten in Ireland, and Steve Borthwick’s boys could fall to another close defeat here. Our money is going on France at 1.47.

France Win – 1.47

Bet on England vs France

Ireland to Secure Second Win

Ireland are many people’s picks to win the Six Nations, and the holders got off to a winning start against England last weekend. Can they follow that up with a victory over Scotland at Murrayfield on Sunday?

The Scots are an unpredictable outfit these days, and Gregor Townsend’s troops started with a home win against Italy. However, Ireland are a different animal, and we are backing the visitors to win by a margin in Edinburgh. You can get 2.09 for the Irish to win -7.5.

Ireland to Win -7.5 – 2.09

Bet on Scotland vs Ireland