Midweek US Open Betting Predictions, Tips & Preview
Our Midweek US Open Predictions See Sinner, Djokovic & Alcaraz Progress
The 2025 US Open at USTA Billie Jean King National Tennis Center continues this week. Jannik Sinner faces Alexander Bublik, Novak Djokovic goes up against Taylor Fritz, and Carlos Alcaraz squares off against Jiri Lehecka.
US Open Betting Picks
Jannik Sinner to Win 3-1 – 3.45
Novak Djokovic to Win -1.5 – 2.00
Carlos Alcaraz to Win 3-0 – 1.62
View Latest US Open OddsChampion to Ease into Last Eight
Defending champion Sinner is back in US Open action on Tuesday, facing Bublik in the fourth round. The world No. 1 has dropped just one set in the United States.
After straight-set victories over Vit Kopriva and Alexei Popyrin, the Italian beat Canadian Denis Shapovalov in four sets in round three. Sinner has looked solid so far and remains the man to beat.
Bublik eased past Marin Cilic and Tristan Schoolkate in his first two matches, but his third-round meeting with Tommy Paul was a thriller. The Kazakstani held his nerve to secure a memorable 3-2 victory.
Bublik will be no pushover in this fourth-round fixture, but the reigning champion should have enough quality in the locker to see him off. The 3-1 Sinner win has caught the eye at 3.45.
Jannik Sinner to Win 3-1 – 3.45
Bet on Sinner vs BublikRecord Slam Winner to Progress to Last Four
Djokovic’s US Open journey continues this week with a quarter-final match against Fritz. The 38-year-old is looking to win this tournament for a fifth time.
After getting the better of Learner Tien, Zachary Svajda, and Cameron Norrie, the sensational Serbian went up against Jan-Lennard Struff in the fourth round. Djokovic won in straight sets to book his place in the quarter-finals.
Fritz has dazzled his home crowd, sealing victories over Emilio Nava, Lloyd Harris, Jerome Kym, and Tomas Machac. However, this will be his toughest challenge yet.
Despite his age, Djokovic continues to be a real force in the men’s game, and the 24-time Grand Slam winner should book his spot in the last four. Back Djokovic to win -1.5 at 2.00.
Novak Djokovic to Win -1.5 – 2.00
Bet on Djokovic vs FritzSpaniard Too Hot to Handle
Lehecka and Alcaraz lock horns this week in a tasty quarter-final in the Big Apple. The Czech has done well to get this far, but the Spaniard is the red-hot favourite to reach the semi-finals.
Lehecka reached an Australian Open quarter-final two years ago, and a win over Alcaraz would signal his best-ever Grand Slam result. However, getting the better of the world No. 2 will be a monumental task for the 23-year-old.
Alcaraz is in tip-top form, reaching the last eight without dropping a single set. The 22-year-old from Murcia is gunning for a sixth major win of his seven-year professional career.
Alcaraz should be too hot for Lehecka to handle in this one, and we fancy the Spaniard to go through without conceding a set. The 3-0 Alcaraz victory is priced at 1.62.
Carlos Alcaraz to Win 3-0 – 1.62
Bet on Djokovic vs Fritz

